Ask Question
15 October, 05:17

Hemophilia is an X-linked recessive disorder (Xh) that is passed through generations and can be traced by using a pedigree. What is the probability that a female child of Charles and Marie would suffer from hemophilia?

a. 0 percent

b. 25 percent

c. 50 percent

d. 100 percent

+1
Answers (1)
  1. 15 October, 06:36
    0
    Since hemophilia is an X-linked recessive disorder, the probability depends on the X alleles.

    So, if father has dominant allele (H), the probability that a female child would suffer from hemophilia (genotype: hh) is 0%, no matter of mother's genotype:

    Father Mother

    Parents: H x Hh

    Daughter: HH or Hh

    Father Mother

    Parents: H x HH

    Daughter: HH

    Father Mother

    Parents: H x hh

    Daughter: Hh or Hh

    But, if the father has recessive allele, the probability that a female child would suffer from hemophilia (genotype: hh) will depend on mother's genotype.

    If mother is dominant homozygous, there will be 0% of possibility:

    Father Mother

    Parents: h x HH

    Daughter: Hh

    If mother is recessive homozygous, the possibility is 100%:

    Father Mother

    Parents: h x hh

    Daughter: hh

    If mother is heterozygous, the possibility is 50%:

    Father Mother

    Parents: h x Hh

    Daughter: Hh or hh
Know the Answer?
Not Sure About the Answer?
Get an answer to your question ✅ “Hemophilia is an X-linked recessive disorder (Xh) that is passed through generations and can be traced by using a pedigree. What is the ...” in 📙 Biology if there is no answer or all answers are wrong, use a search bar and try to find the answer among similar questions.
Search for Other Answers