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22 December, 21:42

If you take into account the amount of ATP generated by ATP synthase per molecule of NADH produced in aerobic respiration, the net number of ATP molecules produced by substrate-level phosphorylation, and the fact that NADH molecules produced in the cytoplasm have to be transported into the mitochondria, what is the predicted energy yield of glycolysis in eukaryotic cells?

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  1. 23 December, 01:21
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    The predicted energy yield of Glycolysis is 8 molecules of ATP.

    Explanation:

    During glycolysis NAD + is reduced to NADH by the conversion of glyceraldehyde 3 phosphate to 1,3 bisphosphoglycerate by the catalytic activity of glyceraldehyde 3 phosphate dehydrogenase.

    In this reaction 2 molecules of NAD + is reduced into 2 molecules of NADH. The 2 molecules of NADH enter into electron transport chain to generate 6 molecules of ATP.

    when 1,3 bisphosphoglycerate is converted 3 phosphoglycerate by Phosphoglycerate kinase resulting in the formation of 2 molecules of ATP.

    From all the above aspects it can be stated that according to the given question the predicted energy yield of Glycolysis in eukaryotic cell is 8 molecules of ATP.
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