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31 October, 14:40

The ribonucleotide reductase is important for converting ribose bases to the deoxy form. This conversion is coupled with the oxidation of which compound?

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  1. 31 October, 15:34
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    Thioredoxin

    Explanation:

    Ribonucleotides serve as precursors for synthesis of deoxyribonucleotides and the reaction is catalyzed by enzyme ribonucleotide reductase. The reduction of a ribonucleotide into deoxyribonucleotide requires a pair of hydrogen atoms.

    These hydrogen atoms are supplied from NADPH via ubiquitous protein thioredoxin. The oxidized form of thioredoxin is reduced back in a reaction catalyzed by thioredoxin reductase.
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