After meiosis in the male primary spermatocyte, the resultant secondary spermatocytes are genetically different than the body's somatic cells. The immune system is inclined to attack this 'foreign' cell. Which of the following contributes to the prevention of auto-immune responses to one's own spermatocytes?

a. The desmosomes of sustentacular cells

b. The blood-testis-barrier

c. The acrosome of the sperm cell

d. All of these choices are correct.

e. None of these choices is correct.

Which of the following contributes to the prevention of auto-immune responses to one's own spermatocytes? b. The blood-testis-barrier

Explanation:

After meiosis in the male primary spermatocyte, the resultant secondary spermatocytes are genetically different than the body's somatic cells. The immune system is inclined to attack this 'foreign' cell.

The blood-testis-barrier is one of the tightes barriers in the mammalian body. It is actually called Sertoli cell barrier, and its main function is to control the environment in which germ cells (spermatocytes, spermatids and sperm) develop by influencing the chemical composition of the luminal fluid. It also prevents passage of cytotoxic agents (bodies or substances that are toxic to cells), so we can consider this a "protective" function. Moreover, it protects the germ cells from blood-borne noxious agents.

Answer: Option B.

The blood testis barrier.

Explanation:

The blood testis barrier is the physical barrier between the blood vessels and seminiferous tubules of human testis. It prevent sperm antigen from contracting systemic and lymph circulations preventing immune response.

After meiosis, the resultant secondary spermatocytes are genetically different from the somatic cells. The blood barrier testis serve as a physical barrier and prevent sperm antigen from contracting systemic and lymph circulation thereby preventing immune response.