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7 July, 08:52

Suppose that in a population the frequency of a particular recessive disease is 1/400. assume the presence of only two alleles: dominant allele (a) and a recessive allele (a) in the population and that the population is at hardy-weinberg equilibrium. what is the frequency of the recessive allele that causes the condition?

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  1. 7 July, 12:02
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    Given:

    Frequency of recessive disease = 1/400

    Under Hardy-Weinbert equilibrium, we assume

    p = frequency of dominant allele

    q = frequency of recessive allele,

    Then frequency of recessive disease=qq, or

    q=sqrt (1/400) = 1/20=0.05

    =>

    p=1-q=1-0.05=0.095

    Answer: frequency of the recessive allele, q, is 1/20, or 0.05, or 5%
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