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2 June, 07:12

the condition marfan syndrome results from the production of abnormal elastin, the main component of elstic fibers. predict the potential consequences of defective elastic fibers

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  1. 2 June, 08:18
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    Marfan's syndrome is a genetic disorder known to affect the connective tissues of the body. Since the connective tissue is widely present in different parts of the body, this disorder produces several abnormalities.

    The potential consequences of defective elastic fibers are:

    1. Scoliosis

    2. Cardiovascular problems such as mitral valve prolapse and aortic aneurysms.

    3. Nearsightedness and blurred vision due to the weakening of the ciliary muscles of the eye.
  2. 2 June, 11:08
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    Protein elastin is used to made elastic fiber, component of connective tissue that found abundant in blood vessels, bones, tendon and skin. The effect should be prominent in those organs.

    Aorta is the biggest artery blood vessels and it need more elasticity to withstand the pressure of the ventricle. Less elasticity makes aorta become enlarged. The bone will lose density and become thinner. The tendon in heart valve will be weaken and might cause the heart valve disease. The skin will lose elasticity, so it will be easier to stretch.
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