The actual duplication of generic material in a cell takes place during

a. anaphase

b. metaphase

c. prophase

d. interphase

e. telophase

d. interphase

Explanation:

The cell cycle has stages namely the interphase and M phase. Interphase is the stage of preparation for nuclear division, which is M phase. Interphase has three stages: G1, S and G2. The G1 and G2 are the phases of cell growth. The S phase of the cell cycle is also called a "synthetic phase". This is because DNA replication occurs in S phase of the interphase of the cell cycle.

Since DNA is genetic material, actual duplication of genetic material occurs in interphase.