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30 July, 10:06

Which of the following statements about Ngb-H64Q is true?

a. Ngb-H64Q has a higher affinity than hemoglobin for carbon monoxide, whereas hemoglobin has a higher affinity than Ngb-H64Q for oxygen.

b. Ngb-H64Q has a higher affinity than hemoglobin for both carbon monoxide and oxygen. However, Ngb-H64Q binds to carbon monoxide with a higher affinity than to oxygen.

c. Ngb-H64Q has a higher affinity for oxygen than it does for carbon monoxide.

d. Ngb-H64Q binds to oxygen and carbon monoxide with equal affinity.

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  1. 30 July, 10:59
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    b. Ngb-H64Q has a higher affinity than hemoglobin for both carbon monoxide and oxygen. However, Ngb-H64Q binds to carbon monoxide with a higher affinity than to oxygen.

    Explanation:

    A study of neuroglobin (Ngb), a hemoglobin-like protein present in the brain, was done at the University of Pittsburgh by a team of researchers. Upon testing the red blood cells of a mouse that contained carbon monoxide, they found that Ngb-H64Q was significantly better at removing CO from hemoglobin than 100-percent oxygen treatment. Hence Ngb-H64Q binds to carbon monoxide with a higher affinity than to oxygen.
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