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4 August, 20:49

Which statement is NOT correct concerning 2,3-bisphosphoglycerate (BPG) ?

A. It is an allosteric modulator.

B. It binds with lower affinity to fetal hemoglobin than to adult hemoglobin.

C. It binds at a distance from the heme groups of hemoglobin.

D. It is normally found associated with the hemoglobin extracted from red blood cells.

E. It increases the affinity of hemoglobin for oxygen.

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  1. 4 August, 22:34
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    E. It increases the affinity of hemoglobin for oxygen.

    Explanation:

    2,3-bisphosphoglycerate is a acid This is three carbon isomer of glycolytic.

    The important about 2,3-bisphosphoglycerate

    1. 2,3-bisphosphoglycerate binds at a distance from the heme groups of hemoglobin.

    2. 2,3-bisphosphoglycerate is an allosteric modulator.

    3. 2,3-bisphosphoglycerate is normally found associated with the hemoglobin extracted from red blood cells.

    4. 2,3-bisphosphoglycerate binds with lower affinity to fetal hemoglobin than to adult hemoglobin.

    So the option E is correct.
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