What Le Chatelier's factors cause an increase in the concentration of Hb (CO) 4 (aq) in the Hb (CO) 4 (aq) + 4O2 (g) Hb (O2) 4 (aq) + 4CO (g)

Hb (CO) 4 (aq) + 4O2 (g) ⇄ Hb (O2) 4 (aq) + 4CO (g)

1) If we increase the concentration of CO (g), the reaction above will proceed in reverse direction to decrease its concentration, according to Le Chatelier principle. Hence more of Hb (CO) 4 (aq) will be formed.

2) If we decrease the concentration of O₂, then also, reaction will proceed in reverse direction. Hence concentration of Hb (CO) 4 (aq) will be increased.