Guillaume de Machaut's most famous composition is:

A. Messe de Nostre Dame.

B. Jeu de Robin et de Marion.

C. Magnus Liber Organum.

D. Sumer is Icumen In.

Guillaume de Machaut's most famous composition is "Messe de Nostre Dame".

Answer: Option A

Explanation:

Guillaume de Machaut was a French poet and composer of medieval origin. Many musicologists understood him the finest and most important composer of the 14th century. Machaut's "Messe de Notre Dame" (Mass of Our Lady) is the most celebrated musical work of the 14th century.

Four-part arrangement of the Ordinary of Mass together with the "Ite, missa est" dismissal rule. The mass setting of Machaut is significant, not because it was the first but because of its spacious dimensions and four-part texture (unusual at the time), because it's specifically built as a musical whole, and because it is a first-rate work by any standard.