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5 February, 03:19

Phosphofructokinase is an important control enzyme in the regulation of cellular respiration. Which of the following statements correctly describes phosphofructokinase activity?

A) It is inhibited by AMP.

B) It is activated by ATP.

C) It is activated by citrate, an intermediate of the citric acid cycle.

D) It catalyzes the conversion of fructose 1,6-bisphosphate to fructose 6-phosphate, an early step of glycolysis.

E) It is an allosteric enzyme.

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  1. 5 February, 05:28
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    The answer is E) It is an allosteric enzyme.

    Phosphofructokinase changes it conformational ensemble when is bound to an effector. This suggests that it is an allosteric enzyme. It is activated by AMP, and inhibited by ATP and citrate. It catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate.
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