The A159E mutation causes an A amino acid to be replaced with an E amino acid (their structures are shown here). What effects do you think the A159E mutation will have on the troponin protein?

Question

Biology

Grace Stanley

23 August, 23:08

The A159E mutation causes an A amino acid to be replaced with an E amino acid (their structures are shown here). What effects do you think the A159E mutation will have on the troponin protein?

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Answers (1)

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Messiah Mcpherson · Answer 1

Due to hydrophilic nature of E amino acid, it will make it self to be exposed on protein surface and will disrupt the structure and potentially the function of troponin.

Explanation:

Since the E amino acid is hydrophilic, it will try to be exposed on the surface of the protein and thus will disrupt the tertiary structure and potentially the function of troponin.