Biochemist Erwin Chargaff was the first to discover that, in DNA, [A] = [T] and [G] = [C]. These equalities are now known as Chargaff's rule. Using Chargaff's rule, determine the percentages of all of the bases in DNA that is 22 % thymine.

Question

Biology

Nyasia Frank

5 September, 13:29

Biochemist Erwin Chargaff was the first to discover that, in DNA, [A] = [T] and [G] = [C]. These equalities are now known as Chargaff's rule. Using Chargaff's rule, determine the percentages of all of the bases in DNA that is 22 % thymine.

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Starbuck · Answer 1

The correct answer will be-

Adenine = 22%

Guanine = 23%

Cytosine = 23%

Explanation:

Erwin Chargaff discovered that purines equal pyrimidines in DNA. This shows that adenine is equal to thymine and cytosine is equal to guanine.

If the DNA sample contains 22% thymine, then the amount of Adenine will be 22%.

To calculate the amount of cytosine and guanine

G+C = 100 - (A+T)

G+C = 100 - (22+22)

G+C = 56%

Amount of C will be = G/2 = 23%

Amount of G will be - 23%

Thus, Adenine = 22%, Guanine = 23% and Cytosine = 23%.