A double-stranded DNA sequence with a higher percentage of G:C base pairs than percentage of A:T base pairs has a higher melting temperature (Tm) primarily because of the more favorable stacking interactions of G:C base pairs to adjacent base pairs compared to the stacking interactions of A:T base pairs to adjacent base pairs.

Question

Biology

Karley Bartlett

14 December, 06:34

A double-stranded DNA sequence with a higher percentage of G:C base pairs than percentage of A:T base pairs has a higher melting temperature (Tm) primarily because of the more favorable stacking interactions of G:C base pairs to adjacent base pairs compared to the stacking interactions of A:T base pairs to adjacent base pairs.

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Answers (1)

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Steve Oneal · Answer 1

Consider this statement as true or false.

Answer: The given statement is True.

Explanation:

The type of bond that exists between G: C is triple hydrogen bond and the type of bond that exists between the A: T is double hydrogen bonds.

The reason G:C bond requires more energy to break the bond between them and a bit less energy is required to break the bonds between A:T.

So, the double stranded DNA molecule has more preferred stacking of G:C bond as compared to A: T bond.