Histone methyltransferases are a class of enzymes that methylate certain amino acid sequences in histone proteins. A research team found that transcription of gene R decreases when histone methyltransferase activity is inhibited. Which scientific claim is most consistent with these findings?

The histone methyltransferases enzymes prevents the access of transcription factors of R gene there by decreasing the activity of R gene.

Explanation:

Histone methyltransferase enzymes perform methylation or demethylation of a DNA sequence of a gene.

These enzymes can get the gene on or off by performing methylation or demethlylation of DNA sequence or gene.

They surround the gene to be transcripted by polyadenylation tail, this prevents the access of transcription factors to the gene, thereby preventing the transcription process and consequently no protein formed.

This way transcription of R gene decreases.

By methylating the DNA sequence it modifies the gene and inhibits transcription thereby decreasing or no enzymatic activity.