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10 September, 12:01

Hutchinson-Gilford progeria is an exceedingly rare human genetic disorder in which there is very early senility and death, usually from coronary artery disease, at an average age of 13 years. Patients, who look very old even as children, do not live to reproduce.

Which of the following represents the most likely assumption? A. There is considerable genetic variation in garden peas. B. Traits are inherited in discrete units and are not the results of "blending."C. Recessive genes occur more frequently in the F1 generation than do dominant ones. D. Genes are composed of DNA.

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  1. 10 September, 12:26
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    Option B, Traits are inherited in discrete units and are not the results of "blending.

    Explanation:

    Hutchinson-Gilford progeria syndrome cause early aging in children and is genetic in nature. It is very rare in nature and causes hardening of arteries which may lead to heart attack or stroke at a young age.

    It is caused by the mutation in the LMNA gene that codes for lmin A which is responsible for shaping the nucleus of the cell. It is an autosomal dominant disease and even a single gene copy can cause this disorder. Every time this disorder is reported, no genetic link or history has been observed till date and it is believed that it occur in an individual with no genetic history for Hutchinson-Gilford progeria syndrome. This leads to a conclusion that every time new mutation occurs in the LMNA gene and hence it remains unblended.

    Hence, option B is correct
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