In addition to direct invasion of the vascular wall by an infectious agent, what pathogenic mechanism is a common cause of vasculitis?

Answer: Immune-mediated inflammation

Explanation:

The immune mediated inflammation is common cause of vasculitis. In this case there are group of conditions or diseases which lack a definitive etiology.

It is characterized by the common inflammatory pathways which leads to inflammation which results due to triggered immune system.

Vasculitis is the inflammation of the blood vessels which can cause change in the thickening, scarring and weakening of the blood vessel.