The first-pass effect occurs with orally administered drugs because a. their absorption is slowed by food. b. drug absorbed into the bloodstream from the stomach goes to the liver on the way to the general circulation. c. a drug must first survive the acidic environment of the stomach. d. salivary enzymes in the mouth begin the process of metabolism.

Question

Biology

Liberty Little

22 October, 03:25

The first-pass effect occurs with orally administered drugs because a. their absorption is slowed by food. b. drug absorbed into the bloodstream from the stomach goes to the liver on the way to the general circulation. c. a drug must first survive the acidic environment of the stomach. d. salivary enzymes in the mouth begin the process of metabolism.

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Answers (1)

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Ahmad Mitchell · Answer 1

Answer: Option B

Explanation:

The first - pass effect occurs with the orally passed drugs. The drugs that are taken orally moves to different parts of the body.

The drug administered inside the body is reduced in concentration before it reaches the systematic circulation of the body.

It can be defined as the loss of fraction of drug during the process of absorption which is related to liver and gut wall.

Hence, the correct answer is option B