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12 February, 11:49

if loss of a control element causes an increase in gene expression, what must be the normal role of that control element? propose a biological explanation for how the loss of such a control element could lead to an increase in gene expression.

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  1. 12 February, 14:39
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    The normal role of this control element can be that of a negative modulator or regulator

    Explanation:

    For example, the lactose operon in the bacteria Escherichia coli is negatively regulated. In lactose absence a represor protein is produced, which inserts in the DNA operator site blocking transcription of structural genes. if for example a mutation affects the synthesis of this repressor, expression of structural genes will increase with no regulation.

    A mutation in the DNA operator site that avoids insertion of the repressor, too.

    A mutation in the gene that codes for the repressor, will also do the job
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