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27 May, 04:56

Would penicillin be expected to have an equal ability to kill both Gram-positive and Gram-negative bacteria? Why or why not?

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  1. 27 May, 08:50
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    No, due to the difference in Peptidoglycan layer

    Explanation:

    Since the mode of operation of the drug penicillin is to prevent the proper build-up of peptidoglycan in the cell wall of bacteria and bursting up its cell wall, Penicillin would have greater effect in killing Gram-negative bacteria with thin layer of peptidoglycan in their cell wall, unlike Gram-positive bacteria with a thick layer of peptidoglycan in their cell wall.
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