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24 May, 23:35

Under which condition (s) would genetic testing for predisposition to an inherited disorder in a minor child be considered reasonable?

a. When the mutation within a family is known and is specific

b. When penetrance is high and the expected onset is middle adulthood

c. When the risk is high and prophylaxis to reduce the severity of the disorder is available

d. When the family pedigree indicates an autosomal-dominant pattern of inheritance

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  1. 25 May, 01:28
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    Answer: c. When the risk is high and prophylaxis to reduce the severity of the disorder is available.

    Explanation:

    The genetic testing is done between the period of 10 to 22 weeks of pregnancy. It utilizes the blood or DNA sample taken from the amniotic fluid or samples of placenta to detect the genetic disease or disorder in a developing fetus.

    It is done in cases of suspected abnormal development in the fetus, or to prevent the development of disease in the fetus and also to reduce the severity of the genetic disorder in the developing fetus.
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