Phosphofructokinase catalyzes the phosphorylation of fructose 6‑phosphate to fructose 1,6‑bisphosphate in glycolysis. Fructose 1,6‑bisphosphatase catalyzes the hydrolysis of fructose 1,6‑bisphosphate to fructose 6‑phosphate in gluconeogenesis. This is the two step reaction between fructose six phosphate and fructose one six bis phosphate. The reaction from fructose six phosphate to fructose one six bis phosphate is catalyzed by frustose one six bis phosphatase. The reverse reaction is catalyzed by phospho fructo kinase. How does fructose 2,6‑bisphosphate (F26BP) affect the activity of the enzymes phosphofructokinase‑1 (PFK) and fructose 1,6‑bisphosphatase (FBPase) ?
a. decreases PFK activity,
b. decreases FBPase activity decreases PFK activity,
c. increases FBPase activity increases PFK activity,
d. decreases FBPase activity increases PFK activity,
e. increases FBPase activity
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Home » Biology » Phosphofructokinase catalyzes the phosphorylation of fructose 6‑phosphate to fructose 1,6‑bisphosphate in glycolysis. Fructose 1,6‑bisphosphatase catalyzes the hydrolysis of fructose 1,6‑bisphosphate to fructose 6‑phosphate in gluconeogenesis.