Glucokinase and hexokinase catalyze the first glycolysis reaction; glucokinase has a higher Km. Which is true? A. hexokinase is always functional and is not regulated by negative feedback B. they are not isozymes C. glucokinase is not a zymogen D. glucokinase becomes active from high levels of fructose

The correct answer is C glucokinase is not a zymogen

Explanation:

zymogens are secreted as inactive enzyme which undergo activation by autocatalysis which deals with the removal of short peptide fragment from that zymogen resulting in the formation of active enzyme.

Foe example chymotrypsin enzyme is secreted as zymogens but not glucokinase.