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13 September, 12:34

Suppose that exposure to a chemical mutagen results in a change in the sequence that alters the 5' end of intron 1 (I₁). What might occur?

a. loss of the gene product

b. loss of E₁

c. premature stop to the mRNA

d. inclusion of I1 in the mRNA

e. exclusion of E2

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  1. 13 September, 15:10
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    d. inclusion of I1 in the mRNA

    Explanation:

    Introns are any nucleotide sequence within the gene that is non-coding and it is usually removed by RNA splicing.

    When an RNA transcript is made, it is considered as pre-mRNA. The pre-RNA contains both the introns and the exons. For it to mature into mRNA, the introns should be spliced and the exons are joined together to form the mRNA.

    A mutation might result to the intron I1 not getting spliced hence it will be included in the mRNA.
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