Which of the following is generally true of an X-linked recessive pedigree?

A. Disease is seen more often in males than females.

B. A pattern of skipped generations is rare.

C. Males are gene carriers.

D. Mothers usually transmit the disease to their daughters.

Option (A).

Explanation:

The inherited disorders have been classified into the autosomal disorders and sex linked disorders. These disorders have been further classified into the dominant and recessive disorder.

The X linked recessive pedigree means that the trait will skip the generation. The disease is passed down from mothers to their sons and male are more affected than female. The heterozygous female acts as a carrier for the X linked recessive trait. The female should be homozygous recessive or have both the X chromosome affected to show the trait.

Thus, the correct answer is option (A).