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BiologyBiology
5 September, 13:18

Tumor suppressor genes and oncogenes are implicated in carcinogenesis. However, one can predict whether a gene potentially encodes for a protein that influences carcinogenesis by examining their mutational profile. You sequence the genome of 4 cancers and identify 3 genes of interest. Which of the following genes has the best potential to an oncogene? tumor 1 tumor 2 tumor 3 tumor 4

Gene A S24F, N465T R33T T345S, G366R P367E, P368Y

Gene B S34R, F360I S34R V254I S34E, T67Y

Gene C S24F, I322E C255I, E344D S34E, P367E

a ... Gene A and C are potential oncogenes

b. Gene B and C are potential oncogenes

c. Gene B is a potential oncogene

d. None of the genes are potential oncogenes

e. All of the genes are potential oncogenes

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Answers (1)
  1. 5 September, 16:25
    0
    Answer: Option A - Gene A and C are potential oncogenes

    Explanation:

    Oncogenes are genes that contribute to the conversion of a normal cell into a cancerous cell when mutated or expressed at high levels.

    From the information provided:

    Gene A S24F, N465T R33T T345S, G366R P367E, P368Y and

    Gene C S24F, I322E C255I, E344D S34E, P367E

    Both gene A and C have two similar sequences which represent potential sites of mutation
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