What are known causes of epigenetic effects, and how do they

relate to cancer?

Drag the terms on the top to the appropriate colons on the

bottom to complete the sentences. Not all terms will be used.

acetylation and/or phosphorylation

silence or activate

heterochromatin

the same

activate

different

euchromatin

oxidation and reduction

silence

methylation

Epigenetic effects can be caused by DNA: : and/or histone:

:. As such, they can: : chromosomes or certain

chromosomal regions and be responsible for parental imprinting or

influencing gene activity in: :. Patterns of

nucleotide demethylation and hypermethylation are often: : when

cancer cells are compared to normal cells.

Epigenetic effects can be caused by DNA heterochromatin and/or histone silence or activate.

As such, they can different chromosomes or certain chromosomal regions and be responsible for parental imprinting or influencing gene activity in oxidation and reduction.

Patterns of nucleotide demethylation and hypermethylation are often activate when cancer cells are compared to normal cells.

Explanation:

Cells acquire various patterns of gene expression during differentiation to adapt to a changing environment. Epigenetic and genetic alterations are considered as two independent mechanisms that participate in the onset and progression of cancer. Epigenetic mechanisms can be as important for biological events as genetic mechanisms, which do not imply a change in the DNA sequence, but do have an important role in the modification of gene expression.