Suppose a geneticist mutates the gene for the poly (A) tail-binding protein (PABP) in an eukaryotic cell line. The resulting mutant protein cannot bind to poly (A) tails. What is the effect of the PABP mutation in the cultured cells? A-Transcription will not occur in the cultured cells, because PABP is an essential transcription factor. B-Translation will not occur in the cultured cells, because mRNAs will be degraded at a greater rate than normal. C-Transcription will occur in the cultured cells, but the resulting transcript will be longer than normal. D-Translation will occur in the cultured cells, but the resulting polypeptide will be longer than normal. E-Replication will not occur in the cultured cells, because PABP determines the location of the origin of replication.

Question

Biology

Lana Suarez

16 October, 14:51

Suppose a geneticist mutates the gene for the poly (A) tail-binding protein (PABP) in an eukaryotic cell line. The resulting mutant protein cannot bind to poly (A) tails. What is the effect of the PABP mutation in the cultured cells? A-Transcription will not occur in the cultured cells, because PABP is an essential transcription factor. B-Translation will not occur in the cultured cells, because mRNAs will be degraded at a greater rate than normal. C-Transcription will occur in the cultured cells, but the resulting transcript will be longer than normal. D-Translation will occur in the cultured cells, but the resulting polypeptide will be longer than normal. E-Replication will not occur in the cultured cells, because PABP determines the location of the origin of replication.

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Answers (2)

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Abbie Ray · Answer 1

(B)

Explanation:

Translation will not occur in the cultured cells, because mRNA will be degraded at a greater rate than normal.

The reason of degradation is that scientist mutated the gene in eukaryotic cell which means translation will only occur in eukaryotic cell not in cultured cell.

Leonardo · Answer 2

The answer is: B-Translation will not occur in the cultured cells, because mRNAs will be degraded at a greater rate than normal

Explanation:

The translation process will not happen in cells that are altered, because messenger RNA (mRNA) breaks down at a much higher rate than normal. In such a way that the PABP protein would bind to the poly A tail of the messenger RNA and this is essential in the stability of the messenger RNA.