Answer the following questions about serine protease structure

andfunction. Explain the significance of the following to the

functionof the serine proteases:

A) the oxyanion hole

B) The catalytic triad

C) Differences in substrate binding pockets that

distinguishchmotrypsin, trysin and elastase.

Explanation: The role of the oxyanion hole in serine protease is: generally established to be in stabilizing high-energy between the transition state by the hydrogen bonding.

B. The catalytic triad role is to provides a paradigm for the structural and chemical features of enzymes that allow them to facilitate a difficult reaction.

C. trypsin is the amino acids that is chosen for.

While Chymotrypsin is the enzyme that selects for the aromatic amino acids.

Trypsin is the enzyme that chose for the basic amino acids I. e lysine and arginine.