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4 May, 19:55

Aldosterone is a hormone that is released by the adrenal cortex when your blood pressure is low. It is a fat-soluble molecule and causes water conservation in the kidneys by causing more sodium pumps to be made when it binds with its receptors. Which of the following would be true about his hormone?

1) Aldosterone has receptors on the plasma membrane of kidney cells and activates a signal transduction pathway.

2) Aldosterone has nuclear receptors inside kidney cells and activates gene expression.

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  1. 4 May, 20:02
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    The correct answer is 2 Aldosterone has nuclear receptors inside the kidney cells and activates gene expression.

    Explanation:

    Aldosterone is a steroid hormone as a result it is lipophilic in nature. Aldosterone is a mineralocorticoid secreted from adrenal cortex.

    As it is lipophilic aldosterone can cross the plasma membrane and binds to the nuclear inside the kidney cell which ultimately result in the genes encoding proteins that stimulate water and Na + ions conservation by the kidneys.
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