Which mutations can a geneticist identify with the G‑banding technique? (A) a nonsense mutation introducing a premature stop codon into a gene on chromosome 5 (B) a reciprocal translocation of parts of chromosome 1 and chromosome 11 (C) a translocation of a region of the short arm between sister chromatids (D) a deletion of half of the long arm of chromosome 20 a single nucleotide (E) substitution in which T replaces C on chromosome 2

Question

Biology

Shyanne Douglas

3 May, 23:31

Which mutations can a geneticist identify with the G‑banding technique? (A) a nonsense mutation introducing a premature stop codon into a gene on chromosome 5 (B) a reciprocal translocation of parts of chromosome 1 and chromosome 11 (C) a translocation of a region of the short arm between sister chromatids (D) a deletion of half of the long arm of chromosome 20 a single nucleotide (E) substitution in which T replaces C on chromosome 2

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Answers (1)

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Dean Bender · Answer 1

The correct answer is options - C) and D).

Explanation:

G banding is a technique that is used in cytogenetics to make a visible karyotype by staining the condensing chromosomes and forms the light and dark bands. These bands obtained due to the difference between light staining and dark staining regions as these regions have different relative proportions or ratios.

This technique is used to identifying the genetic diseases or chromosomal abnormalities such as inversion and translocations due to the dark and light band patterns. GC rich bands are light bands whereas its dark at the AT-rich region.

Thus, the correct answer is C) and D).