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12 June, 10:08

Explain why the change in the way that molecules of b globin interact with each other lead to the sickling of the red blood cells in sickle cell anemia

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  1. 12 June, 10:33
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    The sickle form of the hemoglobin gene is created when an adenine nucleotide is changed to a thymine ... That single amino acid replacement in the - globin protein alters the shape and the chemistry of the hemoglobin molecule, causing it to polymerize and distort the red blood cell into the sickle shape.
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