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Today, 09:18

When is acetyl CoA produced?

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Answers (2)
  1. Today, 12:41
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    the answer is during pyruvate processing

    Explanation:

    just did it on bio ap-ex
  2. Today, 12:52
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    Acetyl CoA is produced at many steps in our body, but mainly its produced by decarboxylation of pyruvate.

    Explanation:

    Acetyl CoA is the gateway molecule to Kreb's Cycle. This molecule can pass from the cytoplasm to mitochondria which can be used in further metabolic processes.

    In case of aerobic respiration, glucose undergoes a metabolic breakdown to produce two molecules of pyruvate and a few NADH and ATP. But this pyruvate cannot enter the mitochondria where the next step i. e Kreb's Cycle is going to take place. This is then taken up by Pyruvate Decarboxylase complex or PDC where pyruvate is acted upon by enzyme Pyruvate Decarboxylase which also uses an oxidized NAD and Coenzyme A to produce a molecule of carbon dioxide, NADH and Acetyl CoA.
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