Once a stop codon is reached, no more tRNAs will bind. What protein will bind instead?

Question

Biology

Amina Ortega

5 October, 09:21

Once a stop codon is reached, no more tRNAs will bind. What protein will bind instead?

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Answers (1)

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Adrienne Lara · Answer 1

Once a stop codon is recognized the so formed protein molecule will bind to one molecule of water in place of tRNA.

Explanation:

During the termination phase of translation when the ribosome recognizes any one of the 3 stop codons such as UAA, UAG and UGA at that time the polypeptide that is formed will get no tRNA to bind.

As a result instead of tRNA a water molecule binds with the growing polypeptide thus tRNA molecule get detached from the polypeptide, the polypeptide is released from the translation machinery by the activity of various protein called release factors.

Then the mRNA and two subunits of ribosome are also released from the translation machinery.