Sign In
Ask Question
Biology
Akira Rowe
23 May, 09:58
What is CAP? How does CAP work?
+5
Answers (
1
)
Tamara Garcia
23 May, 13:50
0
The Escherichia coli catabolite gene activator protein (CAP) is a DNA binding protein involved with the transcription of several genes, including those that code for enzymes involved in the metabolism of certain sugars (i. e. lactose, maltose, and arabinose.) Basically, CAP is responsible for the global regulation of carbon utilization. Upon binding cAMP, CAP binds to a conserved DNA sequence from which it can either activate or repress transcription initiation from various promoters. In some cases clusters of several promoters are all controlled by a single cAMP-CAP complex bound to the DNA.
Once CAP has bound cAMP, the protein exhibits a higher affinity for a specific conserved DNA sequence. When the intracellular level of cAMP increases, the second messenger is bound by CAP and the cAMP-CAP complex binds to the DNA. Once bound, it is able to stimulate the transcription of the aforementioned genes. DNA bound by the CAP-cAMP complex is bent by ~90 degrees. This DNA bend, coupled with a protein-protein interaction between CAP and RNA polymerase is thought to be the mechanism by which CAP regluates transcription initiation on the chromosome.
Comment
Complaint
Link
Know the Answer?
Answer
Not Sure About the Answer?
Get an answer to your question ✅
“What is CAP? How does CAP work? ...”
in 📙 Biology if there is no answer or all answers are wrong, use a search bar and try to find the answer among similar questions.
Search for Other Answers
You Might be Interested in
45. What is thought to be true about the three domains of living things? a. They diverged from a common ancestor fairly recently. b. They diverged from a common ancestor before the evolution of the main groups of eukaryotes. c.
Answers (1)
I want to dig up fossils. I live kinda near the coast of FL. Where should I go to dig up some?
Answers (2)
Corn is a typical c4 plant, associated with open grasslands. a. True b. False
Answers (1)
Which beat describes the brain stem
Answers (1)
Organisms going into hibernation and dying off and leaving their eggs behind is an example of what
Answers (1)
New Questions in Biology
How is the streak test used to identify minerals?
Answers (1)
What kind of bond is formed when 2 atoms form an electron?
Answers (2)
What's a specific cellular process that would be affected by a glucose shortage
Answers (1)
How can the level of pain you feel vary if a stimulus causes an all or none response?
Answers (1)
How long does gunpowder residue remain on a shooter's hands? A few hours About 24 hours A few days About a week
Answers (1)
Home
»
Biology
» What is CAP? How does CAP work?
Sign In
Sign Up
Forgot Password?