What is the risk for a person to inherit an autosomal-dominant genetic disease-causing allele from a parent who is heterozygous if the disorder has a penetrance factor of 75%?

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Biology

Juliette Oneal

28 February, 02:05

What is the risk for a person to inherit an autosomal-dominant genetic disease-causing allele from a parent who is heterozygous if the disorder has a penetrance factor of 75%?

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Elliot Norton · Answer 1

When both parents are carriers for a recessive disorder, each child has a 1 in 4 (25 percent) chance of inheriting the two changed gene copies. A child who inherits two changed gene copies will be "affected," meaning the child has the disorder.