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17 November, 17:52

In assembling a nucleosome, normally the ... (1) histone dimers first combine to form a tetramer, which then further combines with two ... (2) histone dimers to form the octamer.

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  1. 17 November, 21:29
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    option 1

    Explanation:

    In assemblying the nucleosome, this reaction occurs in two main steps. the H3 and H4 are recruited first to the DNA in pairs forming the H3/H4 tetramer; meaning two of H3 and two of H4. This gives rise to the nucleosome precursor. Then after this, the dimers of both H2A/H2B are recruited to this precursor, to give rise to the octamer structure around which the DNA is wrapped.
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