Cyclosporine is a drug sometimes used to prevent transplant rejection after organ transplant surgery. This drug specifically disrupts cell-mediated immunity by cytotoxic T cells. Which of these events can be predicted based on this information?

Question

Biology

Karla Berry

5 December, 18:08

Cyclosporine is a drug sometimes used to prevent transplant rejection after organ transplant surgery. This drug specifically disrupts cell-mediated immunity by cytotoxic T cells. Which of these events can be predicted based on this information?

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Answers (1)

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Savage · Answer 1

Cyclosporine

Explanation:

Antibody production will NOT be disrupted in the recipient in case of Cyclosporine

Cyclosporine belongs to a class of drugs known as immunosuppressants, it works by slowing down body's defense system (immune system) to prevent the body from rejecting a transplanted organ Cyclosporine is used to prevent organ rejection in people who have received a liver, kidney, or heart transplant Cyclosporine is a neutral lipophilic polypeptide with an amino acid side chain, it is an immunomodulatory agent that belongs to the calcineurin inhibitors group and has a major effect in T cell activation Its major ability is to block the activation of the nuclear factor of activated T cells (NF-AT) required for transcription of cytokine genes namely the gene that encodes interleukin-2 (IL-2) IL-2 is a major enhancer for T-cell activation and recruitment