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5 January, 04:32

Sickle cell anemia is a disease that causes red blood cells to clump. It often leads to blood clots and strokes, among other conditions. Sickle cell anemia is due to a recessive allele and nearly all homozygous individuals have the disease, but its effects vary. Some individuals with the disease can live fairly normal lives well into middle age, and others die in infancy. Sickle cell anemia exhibits:

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  1. 5 January, 06:25
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    pleiotropy

    Explanation:

    Pleiotropy is the condition when the gene at a single locus regulates more than one genetic trait or function. The allele for sickle cell anemia is recessive and gives rise to multiple symptoms. Its effects on individuals vary. This single allele gives rise to multiple conditions such as the formation of blood clots, stroke, fever, rapid heart rate, swelling and inflammation of the hands and/or feet, leg ulcers, eye damage. Therefore, sickle cell anemia exhibits pleiotropy.
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