What happens to an enzyme that is in a extreme temperature or pH that it was not meant to be in

Answer: The enzyme coagulate and become inactivated

Explanation:

Since enzymes are proteins, they are sensitive to heat. All enzymes function best at a physiological pH and temperature. At higher temperatures (above 60°c), enzymes coagulate and thus become inactivated, because there occurs an irreversible change in their chemical structure.

google it