Inhibition of ADH

Select all that apply

a. results in edema

b. is triggered by hyponatremia

c. is caused by angiotensin II

d. is caused by alcohon consumption

D. is caused by alcohol consumption

Explanation:

- ADH hormone is also called as vasopressin, it is secreted by the supraoptic nuclei of hypothalamus and released by posterior pituitary.

- The main function of ADH is to stimulate reabsorption of water from kidney tubules i. e DCT (distal convoluted tubules) and collecting duct.

- Anti diuretic means against diuresis (excess urination or loss of water). Insufficient ADH can lead to diabetes insipidus which includes the symptoms such as diuresis and dehydration but no glucose in urine.

- Alcohol suppresses the release of ADH, thus water reabsorption reduces and urine volume increases.

- Very high levels of ADH can result in dangerous conditions such as cerebral edema due to excess fluid buildup in the body.

- ADH allows the kidney to form concentrated urine while excreting normal amounts of salts. Continuous secretion of ADH may lead to hyponatremia i. e decrease of sodium levels in blood.

- Angiotensin II is released when there is low BP and it stimulates release of vasopressin/ADH to cause the vaso-constriction, there by bring the BP to normal.