What is antibody affinity maturation?

affinity maturation-

because antibodies can potentially be generated against millions of unique epitopes, the size of an organisim's genome would need to increase exponentially in order to every possible antigen - binding side.

Description

In immunology, affinity maturation is the process by which TFH cell-activated B cells produce antibodies with increased affinity for antigen during the course of an immune response. With repeated exposures to the same antigen, a host will produce antibodies of successively greater affinities.