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26 November, 12:12

Which noncoding RNAs are correctly matched with their function?

Select all that apply:

a. MicroRNAs (miRNAs) bind to complementary sequences in mRNA and block its translation.

b. Piwi-associated RNAs (piRNAs) reestablish appropriate methylation patterns in the genome during gamete formation.

c. Small interfering RNAs (siRNAs) bind to complementary sequences in mRNA and block its translation.

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  1. 26 November, 14:16
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    a. MicroRNAs (miRNAs) bind to complementary sequences in mRNA and block its translation.

    b. Piwi-associated RNAs (piRNAs) reestablish appropriate methylation patterns in the genome during gamete formation.

    Explanation:

    MicroRNAs

    These are the small non-coding RNA molecule. These RNA consist of about 22 nucleotides. MicroRNAs are found in animals, plants and some viruses,

    MiRNAs function

    MicroRNAs also represented as miRNA function through base-pairing with complementary sequences of mRNA molecules. Due to this base pairing it functions as RNA silencing and regulation of gene expression.

    Piwi-interacting RNA

    piRNA expressed in animal cell. piRNA are the small non-coding RNA molecules which form RNA-protein complexes.

    Piwi-interacting RNA Function:

    Function of these complexes are epigenetic and post-transcriptional silencing of transposons.

    Small interfering RNA:

    siRNA molecules are the small pieces of double-stranded (ds) RNA. There length is about 21 nucleotides long. siRNA have 3' (3 prime) overhangs

    Small interfering RNA Function:

    siRNA overhangs are used to "interfere" protein translation. They perform this function by binding and degradation of mRNA at specific sequences
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