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25 October, 12:27

How can genomic imprinting affect gene expression in mammalian embryos? How can genomic imprinting affect gene expression in mammalian embryos? Lower expression of the maternal allele of a gene relative to the paternal allele may occur if a maternal allele carries less silencing marks (e. g. methylation) than the paternal allele. Higher expression of the maternal allele of a gene relative to the paternal allele may occur if a paternal allele carries more silencing marks (e. g. methylation) than the maternal allele. Higher expression of the maternal allele of a gene relative to the paternal allele may occur if a paternal allele carries less silencing marks (e. g. methylation) than the maternal allele. Lower expression of the maternal allele of a gene relative to the paternal allele may occur if a paternal allele carries more silencing marks (e. g. methylation) than the maternal allele. Request Answer

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  1. 25 October, 16:09
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    Genomic imprinting is an epigenetic phenomenon that causes genes to be expressed in a parent-of-origin-specific manner ... These epigenetic marks are established ("imprinted") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.

    Explanation:

    Genomic imprinting affects a subset of genes in mammals and results in a ... In contrast, nonimprinted genes will be expressed from both parental gene ... Surprisingly, mice carrying the mutant nonfunctional allele showed a ... In contrast, embryos that develop within eggs are unable to directly influence maternal resources.
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