The following is a list of events involved in the activation of a cell by a steroid hormone. Which one of the following answers best represents the order in which the steps occur?

1. cellular response to the hormone

2. activation of a gene

3. formation of a hormone-receptor complex

4. diffusion of the hormone through a target cell membrane

5. production of a protein

diffusion of the hormone through a target cell membrane

formation of a hormone-receptor complex

activation of a gene

cellular response to the hormone

production of a protein

Explanation:

Steriod hormone are primary hormones derived from lipids. Such as reproductive hormones i. e the testosterone and the estrogens, which are produced by the gonads (testes and ovaries). Steroid hormones are not soluble in water (they are hydrophobic). For a new cell to be activated by a steriod hormone, there are a lot of steps invovled, Steriod hormones must travel to their target cell bound to a transport protein (i. e diffusion of the hormone through a target cell membrane).

Once the hormone binds to the receptor in the targeted cell, a chain of events is initiated that leads to the target cell's response (I. e formation of a hormone-receptor complex). Hormones plays a vital role in the regulation of physiological processes because of the target cell responses they regulate.

The message a hormone sends is received by a hormone receptor, (a protein located either inside the cell or within the cell membrane). The receptor will process the message by initiating other signaling events such as (activation of a gene) or cellular mechanisms that result in the target cell's response. Hormone receptors recognize and respond to them (i. e cellular response to the hormone). Thus, the response triggered by a hormone depends not only on the hormone, but also on the target cell.

Once the target cell receives the hormone signal, it can respond in a variety of ways. The response may include the (production of protein synthesis), activation or deactivation of enzymes, alteration in the permeability of the cell membrane, and stimulation of the secretion of products. etc