Which of the following methods are used to absorb drugs through the mucosal membrane?

(A) rectal and vaginal suppositories

(B) buccal (between the gums and cheek)

(C) sublingual (under the tongue)

(D) insufflation (snorting a drug into the nose)

Answer: Option D.

Explanation:

Insufflation is a method which is used as a route of administration for drugs through nasal cavity.

The nasal cavity is having a thin vascularised mucosal layer, therefore during Insufflation when a drug molecule is administered, it transferred quickly across the layers of epithelial cell directly into lymphatic system and starts it"s effect within 5 minutes.

Hence, Insufflation is a method which is used to absorb drugs through mucosal membrane.