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21 June, 14:57

What are two main types of posttranscriptional modifications that take place in the mRNA of eukaryotes? The excision of the introns and the addition of a 7-mG cap to the 3' end. The addition of a poly-T sequence at the 5' end of the gene and the addition of a poly-U tail at the 3' end. The addition of a 7-mG cap at the 5' end of the transcript and the addition of a poly-A sequence at the 3' end of the message. The addition of a poly-A sequence at the 5' end and the addition of a 7-mG cap at the 3' end of the RNA transcript.

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  1. 21 June, 18:31
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    The correct answer is: The addition of a 7-mG cap at the 5' end of the transcript and the addition of a poly-A sequence at the 3' end of the message

    These posttranscriptional processes are called:

    • 5' capping - It protects the mRNA from 5' degradation by exonucleases. Cap is also involved in ribosomal binding.

    • Polyadenilation or addition of poly (A) tail - It also protects mRNA from degradation of 3'exonucleases. A long poly (A) tail can also increase translation.
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