Which of the following statements is FALSE regarding enzymes?

A) Enzymes increase the rate of a reaction.

B) Enzymes lower the activation energy (EA) for a reaction.

C) The substrate for an enzyme binds to the enzyme's active site.

D) Enzymes make nonspontaneous reactions become spontaneous

E) Enzymes are very specific for the substrates they bind to

D) Enzymes make nonspontaneous reactions become spontaneous

Explanation:

Being spontaneous or non-spontaneous in nature depends on the difference in energy levels between substrates and products of the reactions. A reaction with substrates at higher energy levels than the products are spontaneous ones. On the other hand, the reactions wherein products have higher energy content than the substrates are non-spontaneous.

Enzymes do not change the energy levels of substrates and products, so, they can not make a non-spontaneous reaction to become a spontaneous one. Enzymes only lower down the activation energy for a reaction and thereby make the non-spontaneous reaction to occur at a faster rate.