The first lines of defense of the innate immune response are

A. skin

B. mucous membranes

C. ciliated respiratory tract

D. secretions such as tears and saliva which contain enzymes

E. all of the above

All of the above.

Explanation:

The first line of defense of the body may be defined as the defense system that first protect the body from the pathogens. Physical and chemical barrier acts as a first line of defense.

Skin contain protein that protect the body from the pathogen. The mucous membrane and ciliated respiratory tract traps the pathogen. Tears contain lysozyme that provide the defense from the bacteria and saliva kill harmful microorganism that enters in the body.

Thus, the correct answer is option (E).